GSK Reports the Data from the P-III (FIRST-ENGOT-OV44) Study Evaluating Zejula and Jemperli in 1L Advanced Ovarian Cancer
Shots:
- GSK reported data from the P-III (FIRST-ENGOT-OV44)study evaluating Jemperli + SoC Pt.-based CT and Zejula maintenance with or without bevacizumab in 1L treatment of stage III or IV nonmucinous epithelial ovarian cancer
- The study met its 1EP (n=1138) of PFS in Arm 2 (385) evaluating SoC CT followed by Zejula maintenance and in Arm 3 (n=753) evaluating SoC CT and Jemperli followed by Zejula and Jemperli maintenance (Bevacizumab can be added across all the arms)
- The study 2EPs are OS, PFS2, time to first & second subsequent therapy, the key 2EP OS does not meet statistical significance and currently, the study is ongoing, demonstrating a consistent safety and tolerability
Ref: GSK | Image: GSK
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